The song of Pearly-breasted Conebill is described as a "variable, rapid, high jumble of squeaky warbles and sharp chips" (Lane, in Schulenberg et al. 2007). This song typically is arranged in loose phrases, and often given as duets by a pair. It is faster and higher pitched than the otherwise similar song of Bicolored Conebill (Conirostrum bicolor).
For a representative audio recording with sonogram, see audio
The calls are varied, but include a "high teep and ti-ti-ti" (Lane, in Schulenberg 2007). It also utters a high, sharp, doubled tip-tseep, with the second note higher.