There is very little information on the reproductive biology of Masked Flowerpierer. The nest is described as open cup of moss, grass, and plant fibers, lined with feathers, and eggs (clutch size?) are described as pale greenish blue, densely spotted with brown (Sclater and Salvin 1879). Greeney et al. (2010) observed an adult incubating a nest five meters above the ground in an epiphyte clump. Fledglings have been recorded in Venezuela and Colombia in the months of December, March, and April, and in Peru and Bolivia in the months of March, May, July, and December (Fjeldså and Krabbe 1990, Hilty 2011). Immature Masked Flowerpiercers have been recorded year-round (Fjeldså and Krabbe 1990).