Most species in the genus Epinecrophylla are similar to one another: small brown antwrens, the males of which have throats that with a black and white "checkered" pattern. The Checker-throated Antwren is the only member of the genus that occurs west of the Andes; this species is found from Honduras south to northern Colombia and to western Ecuador. Singles, pairs, or family groups forage in the under- and midstory of lowland forest and adjacent second growth, usually as members of mixed species flocks. As is typical of all species of Epinecrophylla, the Checker-throated Antwren searches for arthropods that are hidden in curled, dead leaves that are trapped in vine tangles and other sites above the ground. The nest is a deep cup, usually located within a few meters of the ground. The clutch is two. Juvenile Checker-throated Antwrens follow the parents for up to six months after fledging.