The Stripe-chested Antwren is distributed discontinuously along the east Andean slope, at elevations between 400 and 1800 m, from southern Colombia to northwest Bolivia, where it is represented by some four subspecies. This species is considered to be the sister-species of the Amazonian Brazil endemic, the Klages’s Antwren (Myrmotherula klagesi). The distributions of these two species are allopatric. The two species are very similar, differing principally differ in female plumage, especially in the depth of the color of the underparts, from deep orange to pale buff, although not all of the morphological differences between them appear to be entirely clear. Males are fundamentally black, gray, and white, and heavily streaked, much like many other small Myrmotherula antwrens. The Stripe-chested Antwren generally is fairly common over its largely broad range; the species forages singly or in pairs, and at least occasionally joins mixed-species flocks, the composition of which varies geographically.